BDBM127750 US10251889, Example 123::US10758542, Example 123::US8791123, 123::US9782415, Example 123::US9796724, Example 123

SMILES C[C@@H](NC(=O)c1cnn2ccc(nc12)N1CCC[C@@H]1c1cncc(F)c1)C1CC1

InChI Key InChIKey=HRNZKBRSPYYSBU-FZKQIMNGSA-N

Data  32 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 127750   

TargetTyrosine-protein kinase JAK1 [866-1154](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM127750(US10251889, Example 123 | US10758542, Example 123 ...)
Affinity DataIC50: >1.00E+3nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Jak1 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [866-1154](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM127750(US10251889, Example 123 | US10758542, Example 123 ...)
Affinity DataIC50: >1.00E+3nMAssay Description:Jak1: Compounds of Formula I were screened for their ability to inhibit Jak1 using the general enzyme inhibition assay method, in which the assay mix...More data for this Ligand-Target Pair
In DepthDetails US Patent